S-Glycidol: Uses and Specifications
- Chemical Name: (S)-(-)-Glycidol
- Molecular Formula: C₃H₆O₂
- Molecular Weight: 74.08 g/mol
- CAS Number: 60456-23-7
- Physical State: Liquid
- Appearance: Colorless to yellow clear liquid
- Optical Purity: ≥ 97% ee (chiral GC)
- Purity: ≥ 96% (GC)
- Boiling Point: 67°C at 19 mmHg
- Storage Conditions: Frozen (<0°C) and under inert gas to protect from moisture and heat.
Specifications:
S-Glycidol is a chiral compound, specifically the (S)-(-)-enantiomer of glycidol. It has various applications in organic synthesis, especially in pharmaceutical and fine chemical industries due to its unique structural and stereochemical properties.
Applications
- 1. Chiral Synthesis:
Used in the production of chiral intermediates for prostaglandin and prostacyclin analogues. - 2. Pharmaceutical Research:
Starting material for synthesizing non-peptidic HIV protease inhibitors. - 3. Chemical Reactions:
Functions as a precursor for chiral alcohols and other enantiomerically enriched compounds.
Solubility
Soluble in organic solvents such as chloroform, DMSO, and methanol; also miscible with water.
- S-Glycidol is toxic and poses risks if inhaled, swallowed, or in contact with skin.
It may also be a mutagen and a potential carcinogen. Proper precautions, such as
using in a well-ventilated area and wearing protective equipment, are necessary.
For more detailed information, consult product suppliers like Thermo Fisher Scientific and TCI Chemicals .